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Albumin Electrolytes Explained: Sodium & Chloride in 5% vs 20% Solutions This clip from the Saving Lives Podcast explains that albumin solutions contain electrolytes, not just protein, with a focus on sodium and chloride content. Albumin has a sodium concentration of about 145 ± 15 mmol/L, so giving it to a patient who is already hypernatremic may raise serum sodium. The main variability is in chloride: 5% albumin contains about 128 mmol/L of chloride, while higher-concentration (hyperoncotic) a
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