Mycobacterium tuberculosis infects the respiratory tract and establishes a complex interplay with the host immune system. Upon inhalation, bacilli are phagocytosed by alveolar macrophages but evade ...

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that orchestrate the degradation of extracellular matrix components during Mycobacterium tuberculosis infection. In pulmonary ...

lasma metabolomic analysis in active tuberculosis patients and healthy controls. Cerebral tuberculosis (CTB), a severe and often fatal form of central nervous system (CNS) tuberculosis, poses ...

A histone acetylome-wide associations study (HAWAS) performed in immune cells from patients with active Mycobacterium tuberculosis infection versus those from healthy controls, has for the first time ...

A more accurate understanding of this pathogenic mechanism could provide a target against the bacterium that caused 1.6 million deaths in 2021, along with 10 million new cases of tuberculosis every ...

Down-regulation of plasma exosome-derived apolipoproteins APOA1, APOB, and APOC1 indicates DR-TB status and lipid metabolism regulation in pathogenesis. Group case-controlled study assessed 17 drug ...

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism - the intrinsic link between metabolism in immune ...

Ocular TB is a rare eye disease due to infection from Mycobacterium tuberculosis, the same bacterium that causes tuberculosis, commonly known as TB. TB symptoms usually start in the lungs, but they ...