Hydroxyurea is an oral chemotherapy drug that doctors may prescribe to people with sickle cell disease. It may help prevent complications due to sickle-shaped blood cells clumping together in small ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

Hydroxyurea remains effective over the long term among children with sickle cell disease, real-world data suggested. The average time on hydroxyurea was 5 years, with many children on the therapy for ...

SAN DIEGO -- Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in patients with hemoglobin SC, a milder form of sickle cell disease (SCD), a ...

Please provide your email address to receive an email when new articles are posted on . Three-quarters of women who became pregnant during hydroxyurea therapy had live births. Researchers observed no ...

Researchers have revealed that hydroxyurea significantly reduces infections in children with sickle cell anemia. Their findings enhance strong evidence of hydroxyurea's effectiveness and could ...

Please provide your email address to receive an email when new articles are posted on . Use of hydroxyurea did not reduce ovarian reserve among girls and young women with sickle cell disease.

Hydroxyurea is generally contraindicated in patients with sickle cell disease who become or plan to become pregnant, but post-marketing safety data suggest that treatment continuation is safe. The ...

Fewer ED visits per year and fewer hospital days per year seen in association with hydroxyurea use. HealthDay News — For children with sickle cell anemia (SCA), hydroxyurea has sustained clinical ...

Hydroxyurea, a myelosuppressive agent that has been a standard treatment in sickle cell disease (SCD) for decades, remains effective over the long term in children with the disease, according to a ...