Assembly of HIV-1, which causes AIDS, takes place on the inner plasma membrane leaflet of infected cells, a geometric building process that creates hexamers out of trimers of the viral Gag protein, as ...

Since HIV’s discovery in the 1980s, scientists have come a long way in understanding the different steps required for its assembly and maturation. Researchers knew, for instance, that HIV wraps its ...

Jamil Saad, Ph.D. Jamil Saad, Ph.D., professor in the Department of Microbiology, is the latest winner of the Heersink School of Medicine’s Featured Discovery. This initiative celebrates important ...

But in the case of fighting AIDS, HIV's ability to rapidly mutate, especially its outer coat protein -- the envelope -- poses a special challenge to vaccine development. So too does the fact that the ...

An electronic 96-channel pipette was one of the tools used to scale up and allow the teamto perform over 7,000 parallel experiments that uncovered more than 100 bNAb escapemutations across 15 viral ...