"Dependency" mapping reveals the genetic adaptations cancer cells make to survive. And while this approach is helping identify promising treatment strategies for several cancer types, researchers have ...

The Broad Cancer Dependency Map team adds CRISPR-based data from 342 cancer cell lines to their growing catalog of genetic dependencies in cancer, and a new method for ensuring that data's accuracy.

Researchers on the Broad Institute's Cancer Dependency Map (DepMap) team have released DEMETER2, an upgraded version of an open source software tool that identifies cancer cells' genetic dependencies ...

Hundreds of new priority anti-cancer drug targets, and biomarkers of which cases those drugs might work best, have been identified in a new study, offering a panoramic view of the genetic dependencies ...

Cancer cells are infuriatingly good at surviving when they shouldn’t. The nimble cells are able to adapt to a slew of mutations and molecular errors, persisting and spreading within the body as a ...