When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

Dendritic cells (DCs) have emerged in the field of cancer immunotherapy as the most potent professional antigen-presenting cells capable of triggering adaptive immunity and bolstering innate immune ...

Cancer immunotherapy is a strategy that turns the patient’s own immune cells into a “search-and-destroy” force that attacks the tumor’s cells. The “search” immune cells are the dendritic cells, which ...

Download the latest edition A few weeks before the transplantation surgery, the team filtered white blood cells, called monocytes, from the donor's blood. Those monocytes were then induced to make ...

Silencing mRNA expression in dendritic cells did not impair T‑cell priming, including for SARS‑CoV‑2 antigens, suggesting that cross‑presentation by other cell types is sufficient to initiate immunity ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring ...

Dendritic cells (DCs) in teleost fish are pivotal antigen-presenting cells that bridge the innate and adaptive arms of immunity. Morphologically and functionally analogous to their mammalian ...

The global aquaculture industry faces an urgent need to eliminate antibiotic dependency while sustaining productivity against increasingly complex disease ...