Stanford researchers have shown that blocking a single enzyme called 15-PGDH can regrow lost cartilage in aging mouse knees ...

A new treatment that blocks an aging-related protein restored lost cartilage in old mice and helped prevent arthritis after ...

Combination of growth factor gene-enhanced cartilage matrix synthesis with interleukin-1 receptor antagonist protein (IL-1Ra) abrogation of cartilage matrix degradation may reduce and possibly reverse ...

Just a few millimeters thick, articular cartilage plays a crucial role in our musculoskeletal system, since it is responsible for smooth (in the truest sense of the word) movement. However, the ...

In November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving "dancing molecules," to repair tissues and reverse paralysis after severe spinal ...

In patients with severe osteoarthritis, cartilage can wear so thin that joints essentially transform into bone on bone — without a cushion between. A new therapy that uses synthetic nanofibers to ...

Current intra-articular drug delivery methods do not guarantee sufficient drug penetration into cartilage tissue to reach cell and matrix targets at the concentrations necessary to elicit the desired ...

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

Cartilage injuries are a common clinical issue, often caused by trauma, severe infections, or degenerative joint diseases. The lack of direct blood supply to cartilage and limited access to nutrients ...

Expedition 74 crew members aboard the International Space Station are 3D-printing viable human cartilage tissues inside the ...

Cartilage cells generate more protein components (collagen II and aggrecan) for regeneration when treated with fast-moving dancing molecules (left) compared to slower moving molecules. In November ...

A working group develops strategies for regeneration of articular cartilage and has found that natural cartilage matrix is suitable as a biomaterial for improved cartilage regeneration. Just a few ...