Most genes known to control the cell cycle are mutated in cancer, some of them quite frequently. These include famous genes such as K-ras and p53. One notable exception is the cyclin-dependent kinase ...
Pfizer Inc. has divulged cyclin-dependent kinase 2 (CDK2), 4 (CDK4) and 6 (CDK6) inhibitors reported to be useful for the treatment of cancer.
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