Scientists at The Scripps Research Institute (TSRI) have found that deep brain stimulation (DBS) can greatly reduce the compulsion to use heroin in standard rat models of addiction. Rats that were ...

A widely accepted assumption in the addiction field is that neuroanatomical changes observed in young people who use alcohol or other substances are largely the consequence of exposure to these ...

GLP-1 receptor agonists, already used for Type 2 diabetes and obesity, show promise in reducing alcohol and drug-seeking ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

For people with an addiction, craving—the strong desire for a substance—can affect their decision-making, new research shows. And how craving affects a decision can depend on what's at stake. The ...

A new study published in the journal Neuron provides evidence that the brain stores competing memories of alcohol use and the ...

A study in mouse models demonstrates how cocaine alters hippocampal function, driving relapse, and identifies a possible therapeutic target. Researchers at Michigan State University (MI, USA), led by ...