For decades, cancer research has focused on the dysregulation of various cellular pathways, including transcription, chromatin structure, proliferative signaling, RNA processing, and genomic integrity ...

Researchers use high-resolution imaging to reveal the dynamic structure of biomolecular condensates, shedding light on their role in health and disease. (Nanowerk News) Biomolecular condensates are ...

Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms. These regulatory proteins bind DNA, turn genes on or off, and ...

Researchers are discovering the electrochemical properties of biomolecular condensates which could help in development of cancer or ALS treatments. Much of cell behavior is governed by the actions of ...

Researchers provide a new framework for designing soft materials that mimic a form of molecular organization seen in living systems. (Nanowerk News) Newly developed DNA nanostructures can form ...

Fusion oncoproteins arise when a gene fuses with another gene and acquires new abilities. Such abilities can include the formation of biomolecular condensates, "droplets" of concentrated proteins, DNA ...

Proteins, which fulfil most of the functions in our body by interacting with other proteins, face a dilemma – they move around the cell with 40 million potential interaction partners. Finding the ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...

Novel synthetic biomolecular condensates have been developed that can degrade intracellular oncogenic protein KRAS. Recently, researchers at Northwestern Medicine (IL, USA) developed a synthetic ...

A team of NYU chemists and physicists are using cutting-edge tools—holographic microscopy and super-resolution imaging—to unlock how cells build and grow tiny, dynamic droplets known as biomolecular ...